Scientific Name(s): Morus alba L.Common Name(s): Common mulberry, Mulberry, Pawi bush, Silkworm mulberry, White mulberry. This latest study from Chinese researchers doesn’t change what we know about mulberry extract: for whatever reason, the extract seems to work particularly well in studies on mice. The medical literature includes numerous references for white mulberry use in atherosclerosis, cancer, diabetes, infection, and neurodegenerative disorders. A dose of 1 g of powdered leaf 3 times a day has been used to treat diabetes or high cholesterol. White mulberry is a medium-sized, monoecious, deciduous tree growing to 30 m tall and 1.8 m wide in both temperate and tropical areas. The powdered leaves are most commonly used for medicine. The anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside from white mulberry inhibited the migration and invasion of highly metastatic A549 human lung carcinoma cells.24 The anticancer activity may be associated with decreased expression of matrix matalloprotinase-2 and urokinase-plasminogen activator and enhanced expression of tissue inhibitor of matrix matalloprotinase-2 and plasminogen activator inhibitor. STABILIZES BLOOD SUGAR & LOWERS GLUCOSE LEVELS: Studies and reviews have shown many White Mulberry Leaf Benefits, like the LOWERING OF GLUCOSE LEVELS after taking these Supplements. Immune System Support. The pollen extract may cause airborne-contact urticaria. [500mg per pill, 1-2 Veggie Capsules per serving - Take with 8 Oz glass of water as Dr recommends]. A prenylated flavanone, isolated from an ethyl acetate extract of white mulberry root, exerted cytotoxic activity against rat hepatoma cells with an IC50 of 52.8 mg/mL.7 A white mulberry root bark extract exhibited cytotoxic activity by inducing apoptosis and inhibiting microtubule assembly on K-562, B380 human leukemia cells, and B16 mouse melanoma cells.25 White mulberry leaf extracts inhibited the growth of HL60 human promyelocytic leukemia and multidrug resistance HL60 cells (HL60/VINC and HL60/DOX).26 The anthocyanins from the fruit controlled tumor metastasis and motility of a melanoma murine cancer cell line by (a) inhibiting tumor cell migration, spreading and tissue invasion of tumor cells, (b) inhibiting signaling pathways, and (c) decreasing DNA binding to nuclear factor kappa-B and AP-1.27 Albanol A, from the root bark of white mulberry, induced apoptosis in HL60 cells.28 Albanol A exhibited potent DNA topoisomerase II inhibitory activity (IC50, 22.8 mcM) similar to that of the control etoposide (IC50, 34.5 mcM), which may trigger apoptosis of HL60 cells. The fruit juice has a cooling and laxative property and is used to treat fevers, colds, diarrhea, malaria, amoebiasis, constipation, and intestinal worms (eg, tapeworm).2, 3, The fruits may be eaten fresh and are used in juice, preserves, and stews, 4 and can be fermented into a sweet and sour tasting wine. MIT NUTRA White Mulberry Leaf Extract is a Natural Antioxidant Rich Herbal Supplement With HUGE Benefits! [500mg/capsule] Our Raw Mulberry Leaves Tablets, in veggie capsules are easier to consume than Mulberry Leaf Tea and Mulberry Syrup or Powder ; MADE IN THE USA, in GMP and FDA certified facilities A dose of 1 g of powdered leaf 3 times a day has been used to treat diabetes or high cholesterol. The root bark has cathartic and anthelmintic properties and is bitter in taste. Dietary supplementation of purified quercetin from white mulberry leaves in obese mice led to improved plasma glucose levels and reduced oxidative stress in the liver.47, A human study documented that a single oral dose of 0.8 and 1.2 g of DNJ-enriched powder suppressed the elevation of postprandial blood glucose and secretion of insulin.48 A similar study documented a ratio of 1:10 white mulberry leaf extract to sucrose in suppressing postprandial blood glucose and insulin.49 A review of 2 small trials (n=20 in each) reported significant improvements in acute blood glucose in type 2 diabetics after consumption of 1 g or 3.3 g single doses of mulberry leaf extract compared to controls.72, Morin from white mulberry, at a concentration of 80 mg/kg, exhibited a hypouricemic action and inhibited xanthine oxidase in oxonate-induced hyperuricemic rats.56 The inhibitory activity on urate uptake in rat renal brush border membrane vesicles was more potent than that of the prescription agent probenecid. Because white mulberry may alter blood sugar levels it should be used cautiously with medications (eg, insulin) that lower blood sugar in diabetes. White mulberry may also increase the side effects of cholesterol-lowering medications and should be sued with caution in patients using benzodiazepines, barbiturates, or antidepressants. Due to the White Mulberry Leaf, your steady blood sugar levels may diminish the feelings of hunger. White mulberry may also interact with medications used for gout. White Mulberry is a commonly recognized plant throughout the world, but there are many different species. #1 QUALITY PURE WHITE MULBERRY LEAF EXTRACT 1000mg/serving (10:1). White Mulberry leaf is proven to block the absorption of 25% of the carbs consumed. Avoid use during pregnancy and lactation due to lack of clinical data. A polyherbal Chinese medicine that included white mulberry was administered to rats with alcohol-induced fatty acid livers and improved their liver/body weight, serum triglycerides and total cholesterol, liver triglycerides and total cholesterol, and ALT and AST.54, Antibacterial activity is associated with kuwanon C, mulberrofuran G, and albanol B from mulberry leaves with minimum inhibitory concentrations (MICs) ranging from 5 to 30 mg/mL.2, 7 Chloroform mulberry extracts have antibacterial activity against Bacillus subtilis and acetic acid extracts against Staphylococcus aureus and Escherichia coli. Not known for sure the pollen extract latest medication news, new drug approvals, alerts and.. In fact, the white Mulberry Leaf Tea, Syrup or Powder, there! Supplement is a commonly recognized plant throughout the world purposes only and is bitter in taste is. 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